The WEP resource performs a complete whole-exome sequencing pipeline and provides easy access through interface to intermediate and final results.
The pipeline is composed of several steps:
Through our tool a user can perform the whole analysis without knowing the underlying hardware and software architecture, dealing with both paired and single end data. The interface provides an easy and intuitive access for data submission and user-friendly web pages for annotated variant visualization.
Non-IT mastered users can access through WEP to the most updated and tested whole exome sequencing algorithms, ad-hoc tuned to maximize the quality of variants called while minimizing artifacts and false positives.
BMC Bioinformatics. 2013 Apr 22;14 Suppl 7:S11. doi: 10.1186/1471-2105-14-S7-S11. Epub 2013 Apr 22.
WEP: a high-performance analysis pipeline for whole-exome data.
D'Antonio M, D'Onorio De Meo P, Paoletti D, Elmi B, Pallocca M, Sanna N, Picardi E, Pesole G, Castrignanò T.